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EXPECTED OUTPUT :
 
  • Basic information on species / tissue specific TLR gene expression induced by pathogens / ligands in phylogenetically divergent fishes.
  • Evolutionary relationship of TLR-genes in fish species and mammals.
  • Sequences of novel TLR genes with no mammalian counterpart.
  • Information on signaling network and cross-talk between key TLR-genes and their function in phylogenetically divergent fish species.
  • Induced TLR signaling as an alternative model in augmenting innate immunity in fishes.